文献类型：期刊文献

英文题名：A hazardous boundary of Poly(L-lactic acid) braided stent design: Limited elastic deformability of polymer materials

作者：Li, Junjie[1];Cheng, Jie[1];Hu, Xue[1];Liu, Jiaming[1];Tian, Yuan[1,2];Wu, Gensheng[3];Chen, Li[4];Zhang, Yi[5];Zhao, Gutian[1,6];Ni, Zhonghua[1,6]

第一作者：Li, Junjie

通讯作者：Zhao, GT[1];Ni, ZH[1]

机构：[1]Southeast Univ, Sch Mech Engn, Jiangsu Key Lab Design & Manufacture Micronano Bio, Nanjing 211189, Jiangsu, Peoples R China;[2]Suzhou Inst Nanotech & Nanob, Chinese Acad Sci, Suzhou 215123, Peoples R China;[3]Nanjing Forestry Univ, Sch Mech & Elect Engn, Nanjing 210037, Peoples R China;[4]Henan Univ Econ & Law, Modern Educ Technol Ctr, Zhengzhou 450046, Peoples R China;[5]Southeast Univ, Zhongda Hosp, Ctr Intervent Radiol & Vasc Surg, Med Sch, Nanjing 210044, Peoples R China;[6]Southeast Univ, Sch Mech Engn, 79 Suyuan Ave, Nanjing 211189, Peoples R China

第一机构：Southeast Univ, Sch Mech Engn, Jiangsu Key Lab Design & Manufacture Micronano Bio, Nanjing 211189, Jiangsu, Peoples R China

通讯机构：[1]corresponding author), Southeast Univ, Sch Mech Engn, 79 Suyuan Ave, Nanjing 211189, Peoples R China.

年份：2023

卷号：138

外文期刊名：JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS

收录：;EI(收录号：20225213291473);Scopus(收录号：2-s2.0-85144413026);WOS:【SCI-EXPANDED(收录号:WOS:000925292400001)】；

基金：This work was supported by the open research fund of Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical In- struments, Southeast University (No. KF202104) , the National Key Research and Development Program of China (No. 2018YFA0704102) , and the National Natural Science Foundation of China (No. 51775107) .

语种：英文

外文关键词：Poly(L-lactic acid); Braided stent; Mechanical performance; Simulations; Design parameters

摘要：Poly (L-lactic acid) (PLLA) braided stents, which are expected to replace metal stents, are promising in peripheral vascular therapy due to their superior biocompatibility. Although various design ideas have been proposed and investigated on metal stents, few researches are related to the design theory of PLLA braided stent. In this article, mechanical performance of PLLA braided stents with different parameters was systematically evaluated, and a design theory based on material properties was proposed. Different from metal materials, the risk of filament deformation beyond elastic zone should be evaluated and controlled in PLLA stent design. The findings were obtained through combination study of experiments and simulations. Design parameters, including pitch angle and stent diameter, played a crucial role in mechanical performance of PLLA braided stent. The deformation of PLLA stents with larger pitch angles and stent diameters was in elastic zone and thus presented better mechanical performance with satisfactory resilience. This work could provide meaningful suggestions for preparing bio-resorbable braided stents with suitable design parameters.